How Long Does Lisinopril Stay in Your System?
How Long Does It Take for Lisinopril to Work?
Lisinopril medication is used to treat high blood pressure, improve overall blood flow, and reduce heart attack symptoms. It’s been in use for the last thirty years and is one of the most commonly prescribed medicines for the aforementioned conditions. But, how long does lisinopril stay in your system?

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Lisinopril Half-Life
How Long Does Lisinopril Stay in Lab Tests?
Type of Tests
Withdrawal Symptoms
It’s worth noting that lisinopril abuse doesn’t have the same withdrawal phase as more commonly abused substances such as alcohol. Studies show that many of the symptoms associated with suddenly quitting lisinopril center around worsened heart conditions and blood pressure. Another symptom of stopping this medication is the famed lisinopril cough that can last years after final use.
Metabolism
Lisinopril Usage
Lisinopril therapeutic use happens only with a prescription. While the strength of the drug may vary, it’s commonly taken a max of twice per day. Because the lisinopril half-life is twelve hours, taking it twice a day allows the body to be under its effects constantly.
If a person accidentally takes lisinopril twice in one sitting, they should skip their next dose and resume normal dosage the following day. Lisinopril side effects can manifest after first use. If someone has adverse reactions to the drug, they should consult their doctor. It is worth noting that lisinopril use during pregnancy is not suggested.
How Long Does Lisinopril Stay in Your System?
Because lisinopril is metabolized and binds to only a few enzymes in the body, it isn’t detectable in the system for more than a few days at a time—with the exception of hair tests. This means a doctor is able to start prescribing medication for other illnesses, detox a patient on lisinopril, and more in a fairly short amount of time.
Treatment of Lisinopril Drug Abuse
Lisinopril doesn’t have the same addictive capabilities as other abused substances. Nevertheless, a patient may form a psychological connection to and craving for the drug. In this case, the following are recommended treatment options should addiction occur.

Cognitive-Behavioral Therapy
Cognitive-behavioral therapy, also known as CBT, is used to change a person’s everyday habits and thoughts. Over time, a person gains a deeper perspective of their actions and control over them. This process takes time, but its effects can subsist for years after the last session. CBT also helps teach healthy coping mechanisms for lisinopril withdrawal symptoms and cravings.3
Dialectical Behavior Therapy
Group Therapy
Group therapy is a form of talk therapy where individuals who struggle with addiction can speak freely with like-minded people. It also helps give perspective on what to expect in long-term recovery. All in all, group therapy is a great option for stopping lisinopril and other substances.5
Medication-Assisted Treatment
Medication-assisted treatment, or MAT, helps ease the more severe forms of drug withdrawal and replenish vital nutrients. Plus, the side effects of stopping lisinopril can be counteracted with proper medical care.6
Can You Detox from Lisinopril Faster?
Genetics
Genetics play a factor in how well the body absorbs medicine, but because lisinopril is minimally absorbed in the body, the effects of genetics is limited. That said, genetics do play a big role in how easily a person can form an addiction. In addition, lisinopril withdrawal symptoms may also be more severe in a person genetically inclined to addiction.
Health
Drug Use patterns
Learn More with Concise Recovery
If you find yourself asking how long does lisinopril stay in your system, lisinopril half-life, and lisinopril side effects, then chances are you or someone you know is suffering from addiction. Get the help needed to combat addiction and withdrawal symptoms of lisinopril and other substance abuse. Concise Recovery is here to guide and ease the recovery process. Don’t wait. Reach out today and get help.
Resources
- https://www.ncbi.nlm.nih.gov/books/NBK482230/
- https://www.ncbi.nlm.nih.gov/books/NBK459334/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584580/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963469/
- https://www.ncbi.nlm.nih.gov/books/NBK549812/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302321/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014976/