How Long Does Lyrica Stay in Your System

If you or a loved one are using Lyrica, the following information is important to consider.

Understanding Lyrica

Are you wondering, “how long does Lyrica stay in your system?” Lyrica (pregabalin) was designed as a painkiller for people with nerve pain and seizures and used to treat depression and anxiety. Lyrica affects chemicals in the brain and nerves to reduce mental health symptoms.1

How Long Does Lyrica Stay in Your System


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What Is Lyrica (Pregabalin)?

Lyrica is an oral pain medication. Lyrica is sometimes also referred to as pregabalin, its chemical name. Lyrica’s medical uses are for neuropathic pain such as fibromyalgia and diabetic neuropathy.

The half-life of Lyrica is six to nine hours, and it takes about an hour for Lyrica to begin working in most cases.

Is Lyrica a Controlled Substance?

Lyrica is a controlled substance. In addition, Lyrica is a Schedule V drug, placing it on the lower end for the potential for abuse; however, it’s still possible. The only way Lyrica can be legally obtained is by a special prescription from your doctor.2

How Long Does Lyrica Stay in Your System?

Lyrica stays in your system for up to 90 days, depending on the tissue, although the clinical effect wears off in a matter of hours. The half-life of Lyrica is six to nine hours, and if it’s taken as directed, it will be entirely out of your system in about a week. However, if you take more than the prescribed dosage or if it’s abused, the half-life can be much longer. 3

  • How Long Does Lyrica Stay in Your Urine? Lyrica will remain detectable in your urine for up to three days if you take the recommended dosage and stay off the drug for a few days.
  • How Long Does Lyrica Stay in Your Blood? The blood test for Lyrica can detect the drug in your system up to three days after taking the last dosage.
  • How Long Does Lyrica Stay in Your Hair? An analysis of your hair samples can detect Lyrica for up to three months after your last dosage.
  • How Long Does Lyrica Stay in Your Saliva? At least 24 hours. Lyrica can be detected in your saliva for up to three days after taking the drug.

Factors That Affect How Long Lyrica Stays in Your System

Many factors may alter or impact the way that Lyrica stays in your system, such as:


As you know, metabolism is how you process food and energy. Metabolism also happens at a chemical level in your body. Your metabolism aids in getting rid of Lyrica from your system after it has been taken.


The older you are, the longer it will take for Lyrica to leave your system. The same is true for younger people.


If you take the recommended dosage, Lyrica will leave your system faster than if you take more than the recommended dosage.

Usage Duration

The longer you take Lyrica, the more likely it is that the drug will be detectable in your system for a longer period.

Overall Health

Lyrica is a drug that will be cleared out of your system much faster if you’re healthy. However, if you’re ill, it may take your body longer to get rid of the drug.

Usage Frequency

The longer that you’ve been taking Lyrica, the more likely it is that it will be detectable in your system.

Lyrica Drug Test Type

There are three common methods used to test for the presence of drugs in your system. Each method is generally not as accurate as the other, but all of them can give you some information about whether you’ve been taking Lyrica recently. Depending on what kind of test is performed, your results may differ.

Lyrica Withdrawal and Detox

Lyrica withdrawal can be a complex process that involves overcoming both physical and psychological symptoms of Lyrica use.

How Long Does Lyrica's Withdrawal Last?

Most symptoms will last for about two days, with residual symptoms lingering for up to a month.
How Long Does Lyrica Stay in Your System

Withdrawal Symptoms

Lyrica withdrawal symptoms can include nausea, irritability, anxiety, headache, dizziness, sleepiness, loss of appetite, or seizures. Although Lyrica isn’t a drug that can cause seizures, stopping your use of the drug can trigger seizures while you’re undergoing withdrawal. Other withdrawal symptoms may include tremors, diarrhea, agitation, paranoia, auditory hallucinations, or suicidal thoughts.4

Can You Detox from Lyrica Faster?

You can use specific methods to detox from Lyrica in a shorter period. However, the withdrawal from Lyrica isn’t only due to the drug itself but also due to the additive effects of how you were using it.

Get Treatment for Lyrica and Other Prescription Drugs Addiction

If you’re concerned that you or a loved one may have a problem with Lyrica abuse or are addicted to any kind of prescription drugs, contact us to learn how we can help.

With our help and appropriate drug treatment, it’s possible to overcome an addiction to Lyrica.


An alternative to drug rehab, detoxification is an approach that involves the process of withdrawal for drugs such as Lyrica.

Detoxification from Lyrica should be performed in a medical facility by a professional staff that has experience with Lyrica detox.

Addiction Therapies

Drug addiction therapies that can be performed with your drug treatment include:
  • Group therapy: Group therapy is a method of learning from others who are going through the same struggles as you are.
  • Individual therapy: Individual therapy is a method of learning coping skills in a personal setting. You get the chance to reflect on your addiction and learn how to apply techniques for overcoming it.
  • Relapse prevention training: Relapse prevention training is a method of avoiding relapse.
  • Substance abuse counseling: This type of counseling focuses on changing how you think about drugs, how you react to them, and learning the skills to avoid retaking drugs in the future.

Get Help at Concise Recovery

If you or a loved one are struggling with abusing Lyrica, Concise Recovery may be able to help. We offer inpatient and outpatient programs for drug rehab and alcohol rehab treatment for drug and alcohol addiction.

Our rehab facilities offer a personal and customized approach, crafting a unique recovery program for everyone who comes through our doors. Call us today to find out more information about our programs and how we can help you overcome an addiction to prescription drugs, such as an addiction to Lyrica.